| 2. Round | 25/09/2020 | Senglea Athletics | - | Zejtun Corinthians | 1:1 | ||||
| 3. Round | 30/09/2020 | Hamrun Spartans | - | Senglea Athletics | 3:0 | ||||
| 4. Round | 18/10/2020 | Senglea Athletics | - | Sliema Wanderers | 0:2 |  |
|||
| 5. Round | 21/10/2020 | Floriana FC | - | Senglea Athletics | 1:0 | |
|||
| 6. Round | 24/10/2020 | Senglea Athletics | - | Tarxien Rainbows | 0:5 | ||||
| 7. Round | 01/11/2020 | Valletta FC | - | Senglea Athletics | 2:1 | |
|||
| 8. Round | 22/11/2020 | Senglea Athletics | - | Mosta FC | 1:3 | ||||
| 10. Round | 06/12/2020 | Senglea Athletics | - | Birkirkara FC | 1:2 | |
|||
| 12. Round | 14/12/2020 | St. Luċija FC | - | Senglea Athletics | 4:1 | |
|||
| 14. Round | 06/01/2021 | Gżira United | - | Senglea Athletics | 4:0 | |
|||
| 15. Round | 09/01/2021 | Hibernians FC | - | Senglea Athletics | 3:0 | |
|||
| 13. Round | 12/01/2021 | Senglea Athletics | - | Sirens FC | 0:1 |  |
|||
| 18. Round | 30/01/2021 | Senglea Athletics | - | Hamrun Spartans | 0:1 |
Colombia