| 2. Round | 05/09/2020 | MVV | - | SC Cambuur | 1:7 | ||||
| 3. Round | 11/09/2020 | SC Cambuur | - | Go Ahead Eagles | 0:2 | ||||
| 5. Round | 25/09/2020 | SC Cambuur | - | FC Utrecht (J) | 5:2 | ||||
| 8. Round | 20/10/2020 | NAC Breda | - | SC Cambuur | 0:4 | ||||
| 11. Round | 07/11/2020 | SC Cambuur | - | Jong Ajax | 2:3 | ||||
| 18. Round | 03/01/2021 | FC Eindhoven | - | SC Cambuur | 2:5 | ||||
| 29. Round | 22/03/2021 | SC Cambuur | - | FC Eindhoven | 3:0 | ||||
| 32. Round | 05/04/2021 | SC Cambuur | - | SBV Excelsior | 7:2 | ||||
| 38. Round | 12/05/2021 | SC Cambuur | - | NAC Breda | 3:2 |
Netherlands