| 9. Round | 15/02/2022 | Ghazl Al Mehalla | - | Al Mokawloon | 1:1 | ||||
| 10. Round | 21/02/2022 | Al Mokawloon | - | Smouha Sporting Club | 0:0 | ||||
| 11. Round | 25/02/2022 | Future FC | - | Al Mokawloon | 1:0 |  |
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| 13. Round | 16/03/2022 | El Gouna | - | Al Mokawloon | 1:2 | ||||
| 14. Round | 14/04/2022 | Al Mokawloon | - | Misr lel-Maqasah SC | 1:1 | |
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| 16. Round | 26/04/2022 | Al Mokawloon | - | Ittihad El Iskandary | 1:1 | ||||
| 17. Round | 01/05/2022 | Al Masry Club | - | Al Mokawloon | 0:2 | ||||
| 18. Round | 09/05/2022 | El Sharkia Lel Dokhan | - | Al Mokawloon | 1:1 | ||||
| 22. Round | 17/06/2022 | Ismaily | - | Al Mokawloon | 0:0 | ||||
| 23. Round | 28/06/2022 | Al Mokawloon | - | National Bank SC | 1:1 | ||||
| 24. Round | 12/07/2022 | Zamalek | - | Al Mokawloon | 1:0 | ||||
| 26. Round | 22/07/2022 | Al Mokawloon | - | Ghazl Al Mehalla | 1:0 | ||||
| 27. Round | 27/07/2022 | Smouha Sporting Club | - | Al Mokawloon | 1:1 | |
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| 28. Round | 02/08/2022 | Al Mokawloon | - | Future FC | 0:1 | ||||
| 29. Round | 06/08/2022 | Pyramids FC | - | Al Mokawloon | 1:0 | ||||
| 30. Round | 10/08/2022 | Al Mokawloon | - | El Gouna | 0:0 | ||||
| 32. Round | 23/08/2022 | Al Mokawloon | - | Pharco FC | 2:0 | ||||
| 33. Round | 26/08/2022 | Ittihad El Iskandary | - | Al Mokawloon | 0:1 |
Egypt