| 3. Round | 04/02/2025 | San Francisco FC | - | UMECIT | 0:2 |  |
|||
| 4. Round | 08/02/2025 | UD Universitario | - | UMECIT | 2:2 | |
|||
| 5. Round | 16/02/2025 | UMECIT | - | Herrera FC | 2:1 |  |
|||
| 6. Round | 25/02/2025 | Alianza | - | UMECIT | 0:0 | ||||
| 7. Round | 27/02/2025 | UMECIT | - | Potros del Este | 2:1 | ||||
| 8. Round | 09/03/2025 | UMECIT | - | Árabe Unido | 0:1 | ||||
| 9. Round | 16/03/2025 | Plaza Amador | - | UMECIT | 1:1 | ||||
| 10. Round | 23/03/2025 | Tauro FC | - | UMECIT | 4:2 |  |
|||
| 12. Round | 06/04/2025 | Herrera FC | - | UMECIT | 2:1 | ||||
| 13. Round | 15/04/2025 | UMECIT | - | UD Universitario | 0:2 | ||||
| 14. Round | 28/04/2025 | Veraguas United | - | UMECIT | 2:0 | ||||
| 15. Round | 03/05/2025 | UMECIT | - | San Francisco FC | 2:0 | ||||
| 16. Round | 10/05/2025 | UMECIT | - | Independiente de La Chorrera | 1:1 | |
Panama