| 1. Round | 21/01/2007 | CF América | - | Club San Luis | 4:1 | ||||
| 2. Round | 27/01/2007 | Club San Luis | - | Monarcas Morelia | 1:2 | ||||
| 3. Round | 03/02/2007 | Club San Luis | - | Atlante | 3:0 | ||||
| 4. Round | 11/02/2007 | UANL Tigres | - | Club San Luis | 1:1 | ||||
| 5. Round | 15/02/2007 | Club San Luis | - | Atlas Guadalajara | 1:0 | ||||
| 6. Round | 17/02/2007 | Veracruz (old) | - | Club San Luis | 2:1 | ||||
| 7. Round | 24/02/2007 | Club San Luis | - | Jaguares Chiapas | 1:0 | ||||
| 8. Round | 04/03/2007 | Deportivo Toluca | - | Club San Luis | 1:1 |  |
|||
| 9. Round | 10/03/2007 | Club San Luis | - | Santos Laguna | 2:3 | ||||
| 11. Round | 17/03/2007 | Club San Luis | - | Cruz Azul | 2:0 | |
|||
| 10. Round | 22/03/2007 | CF Pachuca | - | Club San Luis | 3:0 | ||||
| 12. Round | 24/03/2007 | CF Monterrey | - | Club San Luis | 3:2 |  |
|||
| 13. Round | 01/04/2007 | Club San Luis | - | Deportivo Guadalajara | 1:0 | |
|||
| 14. Round | 08/04/2007 | Club Necaxa | - | Club San Luis | 1:2 | ||||
| 15. Round | 14/04/2007 | Club San Luis | - | Gallos Blancos (old) | 1:0 | |
|||
| 16. Round | 22/04/2007 | Pumas UNAM | - | Club San Luis | 1:1 | |
|||
| 17. Round | 28/04/2007 | Club San Luis | - | UAG Tecos | 0:2 | |
Uruguay