| Group A | 14/09/2017 | Villarreal CF | - | FK Astana | 3:1 | ||||
| Group A | 28/09/2017 | FK Astana | - | Slavia Praha | 1:1 |  |
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| Group A | 19/10/2017 | FK Astana | - | Maccabi Tel Aviv | 4:0 | ||||
| Group A | 02/11/2017 | Maccabi Tel Aviv | - | FK Astana | 0:1 | ||||
| Group A | 23/11/2017 | FK Astana | - | Villarreal CF | 2:3 | ||||
| Group A | 07/12/2017 | Slavia Praha | - | FK Astana | 0:1 | ||||
| Round of 32 | 15/02/2018 | FK Astana | - | Sporting CP | 1:3 | |
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| Round of 32 | 22/02/2018 | Sporting CP | - | FK Astana | 3:3 | |
Croatia