| Group 3 | 17/02/2021 | Municipal Limeño | - | Luis Ángel Firpo | 1:1 | ||||
| Group 3 | 20/02/2021 | Jocoro FC | - | Municipal Limeño | 0:0 | ||||
| Group 3 | 06/03/2021 | Municipal Limeño | - | CD Águila | 1:2 |  |
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| Group 3 | 10/03/2021 | Luis Ángel Firpo | - | Municipal Limeño | 1:0 | ||||
| Group 3 | 14/03/2021 | Municipal Limeño | - | Jocoro FC | 2:2 | ||||
| Group B | 21/03/2021 | Santa Tecla FC | - | Municipal Limeño | 1:1 | ||||
| Group B | 21/04/2021 | Municipal Limeño | - | AD Chalatenango | 3:0 | ||||
| Group B | 24/04/2021 | CD Águila | - | Municipal Limeño | 1:1 | ||||
| Group B | 28/04/2021 | Municipal Limeño | - | Sonsonate FC | 1:0 | ||||
| Group B | 01/05/2021 | Isidro Metapán | - | Municipal Limeño | 2:0 | ||||
| Quarter-finals | 05/05/2021 | FAS | - | Municipal Limeño | 2:1 | |
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| Quarter-finals | 09/05/2021 | Municipal Limeño | - | FAS | 2:4 pso |
El Salvador