| 1. Round | 18/01/2025 | ART Municipal Jalapa | - | UNAN Managua | 0:0 | ||||
| 2. Round | 22/01/2025 | Rancho Santana | - | ART Municipal Jalapa | 4:0 |  |
|||
| 3. Round | 25/01/2025 | ART Municipal Jalapa | - | Club Deportivo Ocotal | 2:0 | ||||
| 4. Round | 29/01/2025 | ART Municipal Jalapa | - | H&H Export Sébaco | 0:1 |  |
|||
| 8. Round | 19/02/2025 | ART Municipal Jalapa | - | CD Walter Ferretti | 0:0 | |
|||
| 9. Round | 22/02/2025 | Matagalpa FC | - | ART Municipal Jalapa | 3:3 | ||||
| 11. Round | 09/03/2025 | ART Municipal Jalapa | - | Rancho Santana | 2:0 | |
|||
| 16. Round | 13/04/2025 | ART Municipal Jalapa | - | Diriangén FC | 2:2 | ||||
| 13. Round | 15/04/2025 | H&H Export Sébaco | - | ART Municipal Jalapa | 0:0 | ||||
| 17. Round | 27/04/2025 | CD Walter Ferretti | - | ART Municipal Jalapa | 2:1 | |
Cuba