| 5. Round | 04/09/2010 | Oxford United | - | Morecambe FC | 4:0 | ||||
| 6. Round | 11/09/2010 | Hereford United | - | Oxford United | 0:2 | ||||
| 7. Round | 18/09/2010 | Oxford United | - | Stockport County | 0:1 |  |
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| 8. Round | 25/09/2010 | Crewe Alexandra | - | Oxford United | 1:1 | |
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| 9. Round | 28/09/2010 | Cheltenham Town | - | Oxford United | 1:1 | ||||
| 13. Round | 23/10/2010 | Oxford United | - | Northampton Town | 3:1 | ||||
| 14. Round | 30/10/2010 | Bradford City | - | Oxford United | 5:0 |  |
England