| 2. Round | 26/07/2021 | FK Kolubara | - | Radnik Surdulica | 1:1 | ||||
| 9. Round | 17/09/2021 | FK Metalac | - | FK Kolubara | 3:1 | ||||
| 11. Round | 25/09/2021 | FK Kolubara | - | Radnički Niš | 2:3 | ||||
| 13. Round | 16/10/2021 | FK Kolubara | - | Crvena Zvezda | 1:7 | ||||
| 14. Round | 23/10/2021 | Mladost Lučani | - | FK Kolubara | 3:1 | ||||
| 19. Round | 06/12/2021 | FK Čukarički | - | FK Kolubara | 5:0 | ||||
| 28. Round | 20/03/2022 | Crvena Zvezda | - | FK Kolubara | 3:0 |
Serbia