| 2. Round | 11/08/2020 | MŠK Žilina | - | FC Nitra | 1:2 | ||||
| 3. Round | 15/08/2020 | FC DAC 1904 | - | FC Nitra | 6:0 | ||||
| 4. Round | 22/08/2020 | FC Nitra | - | MFK Ružomberok | 1:1 | ||||
| 5. Round | 29/08/2020 | FK Senica | - | FC Nitra | 0:0 | ||||
| 6. Round | 12/09/2020 | FC Nitra | - | FK Pohronie | 3:1 | ||||
| 7. Round | 19/09/2020 | AS Trenčín | - | FC Nitra | 3:2 | ||||
| 8. Round | 26/09/2020 | FC Nitra | - | ŠKF Sereď | 3:0 |  |
|||
| 9. Round | 03/10/2020 | Spartak Trnava | - | FC Nitra | 0:2 | |
|||
| 10. Round | 17/10/2020 | Zlaté Moravce | - | FC Nitra | 3:1 | ||||
| 11. Round | 24/10/2020 | FC Nitra | - | MFK Zemplín Michalovce | 1:1 |  |
|||
| 12. Round | 01/11/2020 | Slovan Bratislava | - | FC Nitra | 0:1 | ||||
| 13. Round | 08/11/2020 | FC Nitra | - | MŠK Žilina | 0:3 | ||||
| 14. Round | 21/11/2020 | FC Nitra | - | FC DAC 1904 | 0:1 | ||||
| 15. Round | 28/11/2020 | MFK Ružomberok | - | FC Nitra | 3:0 | ||||
| 16. Round | 05/12/2020 | FC Nitra | - | FK Senica | 1:1 | ||||
| 18. Round | 16/12/2020 | FC Nitra | - | AS Trenčín | 1:2 |
Slovakia