| 6. Round | 26/08/2018 | Spartak Trnava | - | MFK Ružomberok | 0:0 | ||||
| 8. Round | 15/09/2018 | Spartak Trnava | - | MŠK Žilina | 1:2 | ||||
| 10. Round | 29/09/2018 | Spartak Trnava | - | Slovan Bratislava | 1:2 | ||||
| 11. Round | 07/10/2018 | Spartak Trnava | - | ŠKF Sereď | 2:1 | ||||
| 12. Round | 20/10/2018 | Spartak Trnava | - | FK Senica | 4:1 | ||||
| 13. Round | 28/10/2018 | Zlaté Moravce | - | Spartak Trnava | 1:1 | ||||
| 14. Round | 03/11/2018 | Spartak Trnava | - | FK Železiarne Podbrezová | 2:0 | ||||
| 15. Round | 11/11/2018 | MFK Zemplín Michalovce | - | Spartak Trnava | 1:0 | ||||
| 16. Round | 24/11/2018 | Spartak Trnava | - | FC Nitra | 2:3 | ||||
| 17. Round | 02/12/2018 | MFK Ružomberok | - | Spartak Trnava | 3:1 | ||||
| 18. Round | 08/12/2018 | Spartak Trnava | - | AS Trenčín | 3:1 |
Slovakia