| 3. Round | 15/05/2010 | Philadelphia Union | - | FC Dallas | 1:1 | ||||
| 3. Round | 21/05/2010 | FC Dallas | - | Los Angeles Galaxy | 0:1 | ||||
| 4. Round | 06/06/2010 | FC Dallas | - | San Jose Earthquakes | 2:0 | ||||
| 4. Round | 27/06/2010 | CD Chivas | - | FC Dallas | 1:2 | ||||
| 5. Round | 04/07/2010 | FC Dallas | - | Kansas City Wizards | 1:0 |  |
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| 5. Round | 12/07/2010 | Seattle Sounders | - | FC Dallas | 1:1 | ||||
| 5. Round | 31/07/2010 | Colorado Rapids | - | FC Dallas | 1:1 | |
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| 7. Round | 05/09/2010 | FC Dallas | - | Toronto FC | 1:0 | ||||
| 7. Round | 12/09/2010 | San Jose Earthquakes | - | FC Dallas | 0:0 | ||||
| 7. Round | 17/09/2010 | FC Dallas | - | New York RB | 2:2 | |
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| 7. Round | 23/09/2010 | FC Dallas | - | New England Revolution | 2:2 | ||||
| 7. Round | 26/09/2010 | Kansas City Wizards | - | FC Dallas | 1:3 |  |
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| 8. Round | 03/10/2010 | FC Dallas | - | Chicago Fire | 3:0 | |
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| 8. Round | 09/10/2010 | FC Dallas | - | Colorado Rapids | 2:2 | ||||
| 8. Round | 17/10/2010 | Real Salt Lake | - | FC Dallas | 2:0 | ||||
| 8. Round | 25/10/2010 | Los Angeles Galaxy | - | FC Dallas | 2:1 |
Honduras