| 1. Round | 29/08/2021 | Bnei Sachnin FC | - | Maccabi Tel Aviv | 3:1 |  |
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| 2. Round | 11/09/2021 | Maccabi Tel Aviv | - | Maccabi Petach-Tikva | 1:1 | ||||
| 4. Round | 25/09/2021 | Hapoel Be'er Sheva | - | Maccabi Tel Aviv | 2:0 | ||||
| 5. Round | 03/10/2021 | Maccabi Tel Aviv | - | Hapoel Jerusalem | 1:0 | |
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| 8. Round | 30/10/2021 | Ironi Kiryat Shmona | - | Maccabi Tel Aviv | 1:3 | ||||
| 9. Round | 07/11/2021 | Maccabi Tel Aviv | - | Hapoel Tel Aviv | 1:1 | ||||
| 14. Round | 22/12/2021 | Maccabi Tel Aviv | - | Bnei Sachnin FC | 1:1 | ||||
| 15. Round | 27/12/2021 | Maccabi Petach-Tikva | - | Maccabi Tel Aviv | 1:2 |  |
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| 16. Round | 03/01/2022 | Maccabi Haifa | - | Maccabi Tel Aviv | 3:2 | ||||
| 17. Round | 08/01/2022 | Maccabi Tel Aviv | - | Hapoel Be'er Sheva | 1:0 | |
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| 18. Round | 15/01/2022 | Hapoel Jerusalem | - | Maccabi Tel Aviv | 1:3 |  |
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| 21. Round | 05/02/2022 | Maccabi Tel Aviv | - | Ironi Kiryat Shmona | 1:0 | ||||
| 23. Round | 20/02/2022 | Maccabi Tel Aviv | - | Hapoel Haifa | 2:0 | ||||
| 25. Round | 07/03/2022 | Maccabi Tel Aviv | - | Beitar Jerusalem | 3:1 | |
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| 26. Round | 12/03/2022 | Hapoel Hadera | - | Maccabi Tel Aviv | 0:2 |
Israel
Portugal