| 19. Round | 07/01/2023 | KV Oostende | - | RFC Seraing | 1:2 | ||||
| 20. Round | 14/01/2023 | KV Mechelen | - | KV Oostende | 2:1 |  |
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| 21. Round | 18/01/2023 | KV Oostende | - | Royal Antwerp FC | 0:3 | ||||
| 22. Round | 21/01/2023 | KV Oostende | - | Cercle Brugge | 1:2 | ||||
| 23. Round | 28/01/2023 | KV Kortrijk | - | KV Oostende | 2:2 | ||||
| 24. Round | 03/02/2023 | KV Oostende | - | RSC Anderlecht | 0:2 | |
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| 25. Round | 12/02/2023 | SV Zulte Waregem | - | KV Oostende | 1:1 | ||||
| 26. Round | 18/02/2023 | KV Oostende | - | Sporting Charleroi | 0:0 | ||||
| 27. Round | 25/02/2023 | KRC Genk | - | KV Oostende | 3:0 | ||||
| 28. Round | 03/03/2023 | KV Oostende | - | Club Brugge KV | 3:0 | |
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| 29. Round | 11/03/2023 | KAS Eupen | - | KV Oostende | 4:4 |  |
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| 30. Round | 18/03/2023 | KV Oostende | - | KVC Westerlo | 1:2 | ||||
| 31. Round | 01/04/2023 | KV Oostende | - | Standard Liège | 1:3 | ||||
| 32. Round | 09/04/2023 | Sint-Truidense VV | - | KV Oostende | 5:0 | |
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| 33. Round | 15/04/2023 | KV Oostende | - | Oud-Heverlee Leuven | 0:4 | ||||
| 34. Round | 23/04/2023 | KAA Gent | - | KV Oostende | 1:2 |
Croatia