| 7. Round | 26/10/2020 | Real España | - | Platense | 3:2 |  |
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| 8. Round | 29/10/2020 | Honduras Progreso | - | Real España | 0:3 | ||||
| 9. Round | 02/11/2020 | Real España | - | Marathón | 0:1 | |
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| 13. Round | 15/11/2020 | Lobos UPNFM | - | Real España | 1:1 | |
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| 10. Round | 21/11/2020 | Vida | - | Real España | 2:2 |  |
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| 6. Round | 07/12/2020 | Olimpia | - | Real España | 1:0 |
Uruguay