| 8. Round | 17/10/2010 | 1899 Hoffenheim | - | Bor. Mönchengladbach | 3:2 | ||||
| 17. Round | 18/12/2010 | VfL Wolfsburg | - | 1899 Hoffenheim | 2:2 | ||||
| 18. Round | 15/01/2011 | Werder Bremen | - | 1899 Hoffenheim | 2:1 |  |
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| 20. Round | 29/01/2011 | FC Schalke 04 | - | 1899 Hoffenheim | 0:1 | ||||
| 21. Round | 05/02/2011 | 1899 Hoffenheim | - | 1. FC Kaiserslautern | 3:2 | ||||
| 24. Round | 26/02/2011 | 1899 Hoffenheim | - | 1. FSV Mainz 05 | 1:2 | ||||
| 25. Round | 05/03/2011 | Bor. Mönchengladbach | - | 1899 Hoffenheim | 2:0 | ||||
| 26. Round | 12/03/2011 | 1899 Hoffenheim | - | Borussia Dortmund | 1:0 | ||||
| 34. Round | 14/05/2011 | 1899 Hoffenheim | - | VfL Wolfsburg | 1:3 |
Germany