| 1. Round | 18/09/2021 | SP Cailungo | - | FC Fiorentino | 0:3 | ||||
| 2. Round | 25/09/2021 | FC Domagnano | - | SP Cailungo | 3:0 | ||||
| 3. Round | 03/10/2021 | SP Cailungo | - | SS Pennarossa | 1:2 |  |
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| 4. Round | 17/10/2021 | SP Tre Penne | - | SP Cailungo | 2:1 |  |
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| 5. Round | 20/10/2021 | SP Cailungo | - | SS Folgore/Falciano | 1:2 | ||||
| 6. Round | 23/10/2021 | SS San Giovanni | - | SP Cailungo | 0:0 | ||||
| 7. Round | 30/10/2021 | SS Murata | - | SP Cailungo | 2:1 | |
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| 9. Round | 21/11/2021 | SP La Fiorita | - | SP Cailungo | 2:1 | ||||
| 10. Round | 27/11/2021 | SP Cailungo | - | SP Tre Fiori | 2:3 | |
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| 11. Round | 04/12/2021 | AC Libertas | - | SP Cailungo | 1:1 | |
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| 12. Round | 12/12/2021 | SP Cailungo | - | SS Cosmos | 2:1 | ||||
| 13. Round | 18/12/2021 | SS Virtus | - | SP Cailungo | 0:0 | |
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| 19. Round | 05/02/2022 | SP Cailungo | - | SP Tre Penne | 1:2 | |
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| 20. Round | 12/02/2022 | SS Folgore/Falciano | - | SP Cailungo | 0:1 | |
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| 21. Round | 15/02/2022 | SP Cailungo | - | SS San Giovanni | 1:1 | ||||
| 22. Round | 19/02/2022 | SP Cailungo | - | SS Murata | 0:0 | ||||
| 14. Round | 22/02/2022 | AC Juvenes/Dogana | - | SP Cailungo | 0:4 | |
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| 17. Round | 05/04/2022 | SP Cailungo | - | FC Domagnano | 1:1 | |
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| 29. Round | 13/04/2022 | SP Cailungo | - | AC Juvenes/Dogana | 2:2 | |
Italy