| 1. Round | 17/07/2021 | Academia Cantolao | - | Sporting Cristal | 2:4 |  |
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| 3. Round | 30/07/2021 | Academia Cantolao | - | Ayacucho FC | 2:2 | ||||
| 4. Round | 05/08/2021 | Alianza Lima | - | Academia Cantolao | 2:1 | ||||
| 6. Round | 15/08/2021 | Alianza Universidad | - | Academia Cantolao | 0:3 |  |
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| 7. Round | 19/08/2021 | Universidad San Martín | - | Academia Cantolao | 0:2 | ||||
| 9. Round | 28/08/2021 | Universitario de Deportes | - | Academia Cantolao | 2:2 | ||||
| 12. Round | 23/09/2021 | Academia Cantolao | - | Deportivo Binacional | 1:2 | ||||
| 13. Round | 27/09/2021 | Cusco FC | - | Academia Cantolao | 3:2 | ||||
| 15. Round | 16/10/2021 | Alianza Atlético | - | Academia Cantolao | 3:1 | ||||
| 16. Round | 22/10/2021 | Academia Cantolao | - | Universidad Técnica | 2:0 |
Argentina
Ecuador