| 1. Round | 19/08/2017 | Boston River | - | Plaza Colonia | 3:0 | ||||
| 4. Round | 12/09/2017 | Racing | - | Boston River | 1:1 | ||||
| 5. Round | 18/09/2017 | Boston River | - | El Tanque Sisley | 1:0 |  |
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| 6. Round | 23/09/2017 | Liverpool | - | Boston River | 1:2 | ||||
| 7. Round | 15/10/2017 | Boston River | - | CA Cerro | 1:0 | |
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| 13. Round | 22/11/2017 | Sud América | - | Boston River | 1:0 | ||||
| 14. Round | 25/11/2017 | Boston River | - | Juventud de Las Piedras | 3:1 | ||||
| 15. Round | 03/12/2017 | Danubio | - | Boston River | 1:0 |
Uruguay