| 1. Round | 12/08/2000 | RAA La Louviére | - | Sporting Lokeren | 0:0 | ||||
| 2. Round | 19/08/2000 | Sporting Lokeren | - | Germinal Beerschot | 2:0 | ||||
| 3. Round | 27/08/2000 | Club Brugge KV | - | Sporting Lokeren | 3:1 | ||||
| 6. Round | 16/09/2000 | Sporting Lokeren | - | Sint-Truidense VV | 2:1 | ||||
| 32. Round | 05/05/2001 | Sporting Lokeren | - | Excelsior Mouscron | 2:1 | ||||
| 33. Round | 12/05/2001 | Sporting Lokeren | - | KRC Harelbeke | 3:0 | ||||
| 34. Round | 20/05/2001 | Standard Liège | - | Sporting Lokeren | 0:5 |
Belgium