| 2. Round | 16/01/2022 | LD Alajuelense | - | Guadalupe | 1:0 | ||||
| 3. Round | 22/01/2022 | LD Alajuelense | - | AD Guanacasteca | 4:0 | ||||
| 4. Round | 04/02/2022 | Municipal Pérez Zeledón | - | LD Alajuelense | 2:1 | ||||
| 5. Round | 10/02/2022 | LD Alajuelense | - | CS Cartaginés | 3:2 | ||||
| 6. Round | 13/02/2022 | LD Alajuelense | - | Deportivo Saprissa | 0:1 | ||||
| 1. Round | 17/02/2022 | Sporting FC | - | LD Alajuelense | 2:1 | ||||
| 20. Round | 09/05/2022 | LD Alajuelense | - | CS Herediano | 2:1 | ||||
| 21. Round | 13/05/2022 | LD Alajuelense | - | AD San Carlos | 1:0 | ||||
| 22. Round | 16/05/2022 | Santos de Guápiles | - | LD Alajuelense | 2:0 |
Costa Rica
Colombia