| 7. Round | 10/09/2010 | NK Osijek | - | HNK Šibenik | 3:1 | ||||
| 8. Round | 17/09/2010 | NK Inter Zaprešić | - | NK Osijek | 1:0 | ||||
| 10. Round | 02/10/2010 | RNK Split | - | NK Osijek | 1:0 | ||||
| 11. Round | 16/10/2010 | NK Osijek | - | Dinamo Zagreb | 1:3 | ||||
| 16. Round | 20/11/2010 | NK Osijek | - | HNK Cibalia | 1:0 | ||||
| 17. Round | 27/11/2010 | Hajduk Split | - | NK Osijek | 2:1 |  |
 |
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| 18. Round | 04/12/2010 | NK Osijek | - | NK Zagreb | 0:0 |
Croatia