| 1. Round | 16/12/2020 | JS Kairouan | - | Club Africain | 1:2 | ||||
| 2. Round | 23/12/2020 | Olympique Béja | - | JS Kairouan | 1:1 | ||||
| 11. Round | 30/01/2021 | CA Bizertin | - | JS Kairouan | 0:0 | ||||
| 12. Round | 03/02/2021 | JS Kairouan | - | CS Sfaxien | 0:4 | ||||
| 13. Round | 07/02/2021 | US Tataouine | - | JS Kairouan | 3:1 | ||||
| 6. Round | 17/02/2021 | JS Kairouan | - | Espérance de Tunis | 0:3 | ||||
| 14. Round | 27/02/2021 | Club Africain | - | JS Kairouan | 4:2 | ||||
| 15. Round | 03/03/2021 | JS Kairouan | - | Olympique Béja | 0:1 | ||||
| 16. Round | 07/03/2021 | Stade Tunisien | - | JS Kairouan | 2:0 | ||||
| 17. Round | 10/03/2021 | JS Kairouan | - | ES Métlaoui | 1:1 | ||||
| 18. Round | 14/03/2021 | JS Kairouan | - | AS Rejiche | 0:1 | ||||
| 22. Round | 03/04/2021 | JS Kairouan | - | US Ben Guerdane | 1:3 | ||||
| 23. Round | 07/04/2021 | Étoile du Sahel | - | JS Kairouan | 5:1 |  |
|||
| 19. Round | 18/04/2021 | Espérance de Tunis | - | JS Kairouan | 3:1 |  |
|||
| 24. Round | 05/05/2021 | JS Kairouan | - | CA Bizertin | 1:4 |
Tunisia