| 19. Round | 02/05/2021 | Zamalek | - | Pyramids FC | 1:1 | ||||
| 20. Round | 06/05/2021 | Zamalek | - | Smouha Sporting Club | 2:1 | ||||
| 21. Round | 10/05/2021 | Al Ahly SC | - | Zamalek | 1:1 | ||||
| 22. Round | 14/05/2021 | Zamalek | - | ENPPI | 3:1 | ||||
| 23. Round | 20/05/2021 | Zamalek | - | Tala'ea El Gaish SC | 2:1 | ||||
| 24. Round | 24/05/2021 | Zamalek | - | Al Masry Club | 3:2 | ||||
| 25. Round | 30/05/2021 | El Gouna | - | Zamalek | 0:0 |
Egypt