| 1. Round | 19/10/2022 | Zamalek | - | Smouha Sporting Club | 2:0 | ||||
| 2. Round | 23/10/2022 | Ceramica Cleopatra | - | Zamalek | 0:2 |  |
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| 4. Round | 02/11/2022 | ENPPI | - | Zamalek | 1:1 | ||||
| 6. Round | 07/12/2022 | Tala'ea El Gaish SC | - | Zamalek | 0:4 | ||||
| 3. Round | 11/12/2022 | Zamalek | - | Pyramids FC | 1:0 | ||||
| 7. Round | 16/12/2022 | National Bank SC | - | Zamalek | 0:1 | |
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| 8. Round | 20/12/2022 | Zamalek | - | Haras El Hodood | 4:0 | ||||
| 9. Round | 25/12/2022 | Al Mokawloon | - | Zamalek | 0:0 | ||||
| 10. Round | 29/12/2022 | Zamalek | - | Ismaily | 3:1 | ||||
| 11. Round | 02/01/2023 | Aswan SC | - | Zamalek | 2:1 | ||||
| 12. Round | 05/01/2023 | Zamalek | - | El Daklyeh | 1:1 | ||||
| 13. Round | 11/01/2023 | Ittihad El Iskandary | - | Zamalek | 0:0 | ||||
| 14. Round | 21/01/2023 | Zamalek | - | Al Ahly SC | 0:3 | ||||
| 15. Round | 24/01/2023 | Ghazl Al Mehalla | - | Zamalek | 2:1 | ||||
| 16. Round | 29/01/2023 | Zamalek | - | Future FC | 2:1 | ||||
| 17. Round | 06/02/2023 | Pharco FC | - | Zamalek | 3:0 |
Egypt