| 2. Round | 13/12/2020 | US Tataouine | - | CS Sfaxien | 0:0 | ||||
| 3. Round | 19/12/2020 | CS Sfaxien | - | Club Africain | 3:0 |  |
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| 5. Round | 01/01/2021 | CS Sfaxien | - | Stade Tunisien | 3:0 | |
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| 7. Round | 10/01/2021 | US Ben Guerdane | - | CS Sfaxien | 1:0 | ||||
| 8. Round | 13/01/2021 | CS Sfaxien | - | Espérance de Tunis | 2:0 | ||||
| 9. Round | 23/01/2021 | CA Bizertin | - | CS Sfaxien | 1:1 | ||||
| 10. Round | 26/01/2021 | CS Sfaxien | - | ES Métlaoui | 2:1 | |
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| 12. Round | 03/02/2021 | JS Kairouan | - | CS Sfaxien | 0:4 | ||||
| 13. Round | 07/02/2021 | CS Sfaxien | - | AS Rejiche | 1:0 | ||||
| 4. Round | 16/02/2021 | Olympique Béja | - | CS Sfaxien | 1:0 | ||||
| 6. Round | 28/02/2021 | Étoile du Sahel | - | CS Sfaxien | 0:1 | ||||
| 15. Round | 04/03/2021 | CS Sfaxien | - | US Tataouine | 1:2 | ||||
| 16. Round | 07/03/2021 | Club Africain | - | CS Sfaxien | 0:0 | |
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| 23. Round | 07/04/2021 | ES Métlaoui | - | CS Sfaxien | 0:1 | ||||
| 17. Round | 14/04/2021 | CS Sfaxien | - | Olympique Béja | 0:0 | |
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| 21. Round | 25/04/2021 | Espérance de Tunis | - | CS Sfaxien | 0:0 | ||||
| 22. Round | 02/05/2021 | CS Sfaxien | - | CA Bizertin | 0:0 | ||||
| 25. Round | 09/05/2021 | CS Sfaxien | - | JS Kairouan | 2:0 | |
Tunisia