| 5. Round | 07/11/2021 | Olympique Béja | - | AS Rejiche | 1:2 |  |
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| 6. Round | 19/11/2021 | Étoile du Sahel | - | AS Rejiche | 1:1 |  |
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| 7. Round | 22/11/2021 | AS Rejiche | - | AS Soliman | 2:2 | ||||
| 8. Round | 20/02/2022 | AS Rejiche | - | Club Africain | 0:1 | ||||
| 9. Round | 27/02/2022 | US Monastir | - | AS Rejiche | 0:1 | ||||
| 10. Round | 09/03/2022 | AS Rejiche | - | Espérance Zarzis | 1:0 | ||||
| 11. Round | 13/03/2022 | CS Chebba | - | AS Rejiche | 0:1 | ||||
| 12. Round | 06/04/2022 | AS Rejiche | - | Olympique Béja | 0:0 |
Tunisia