| 7. Round | 18/09/2021 | Olympique Lyonnais B | - | Aubagne FC | 3:1 |  |
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| 8. Round | 25/09/2021 | Jura Sud | - | Olympique Lyonnais B | 1:1 |  |
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| 9. Round | 09/10/2021 | Olympique Lyonnais B | - | Olympique Marseille B | 2:2 | ||||
| 12. Round | 20/11/2021 | Olympique Lyonnais B | - | RC Grasse | 1:0 | ||||
| 17. Round | 05/02/2022 | GFA Rumilly Vallières | - | Olympique Lyonnais B | 0:0 | ||||
| 18. Round | 12/02/2022 | Olympique Lyonnais B | - | AS Saint-Priest | 0:0 | ||||
| 20. Round | 05/03/2022 | Olympique Lyonnais B | - | GOAL FC | 0:2 | ||||
| 27. Round | 29/04/2022 | Olympique Lyonnais B | - | Louhans-Cuiseaux | 2:0 | |
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| 30. Round | 28/05/2022 | AS Monaco B | - | Olympique Lyonnais B | 4:1 |
France
Morocco