| 9. Round | 03/02/2021 | Misr lel-Maqasah SC | - | Ittihad El Iskandary | 0:4 |  |
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| 12. Round | 07/02/2021 | Zamalek | - | Ittihad El Iskandary | 2:0 | ||||
| 11. Round | 11/02/2021 | Ittihad El Iskandary | - | Ismaily | 1:0 | ||||
| 8. Round | 21/02/2021 | Ittihad El Iskandary | - | Aswan SC | 1:3 | ||||
| 4. Round | 01/03/2021 | Ittihad El Iskandary | - | ENPPI | 0:1 | ||||
| 15. Round | 05/03/2021 | Ittihad El Iskandary | - | El Entag El Harby | 2:0 | ||||
| 10. Round | 09/03/2021 | Ittihad El Iskandary | - | Ghazl Al Mehalla | 0:0 | ||||
| 20. Round | 06/05/2021 | Ittihad El Iskandary | - | Al Ahly SC | 1:2 | |
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| 21. Round | 09/05/2021 | ENPPI | - | Ittihad El Iskandary | 0:0 | ||||
| 22. Round | 15/05/2021 | Ittihad El Iskandary | - | Tala'ea El Gaish SC | 1:1 | ||||
| 23. Round | 20/05/2021 | Al Masry Club | - | Ittihad El Iskandary | 1:0 | ||||
| 24. Round | 25/05/2021 | Ittihad El Iskandary | - | El Gouna | 0:1 | ||||
| 25. Round | 28/05/2021 | Aswan SC | - | Ittihad El Iskandary | 0:2 | |
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| 26. Round | 17/06/2021 | Ittihad El Iskandary | - | Misr lel-Maqasah SC | 2:1 | ||||
| 27. Round | 25/06/2021 | Ghazl Al Mehalla | - | Ittihad El Iskandary | 1:1 |
Egypt