| 2. Round | 04/05/2022 | US Ben Guerdane | - | Club Africain | 0:1 | ||||
| 6. Round | 22/05/2022 | Étoile du Sahel | - | US Ben Guerdane | 3:0 | ||||
| 7. Round | 26/05/2022 | Club Africain | - | US Ben Guerdane | 2:1 |  |
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| 8. Round | 19/06/2022 | US Ben Guerdane | - | CS Sfaxien | 0:1 | ||||
| 10. Round | 26/06/2022 | Espérance de Tunis | - | US Ben Guerdane | 2:1 |
Tunisia