| 4. Round | 03/11/2021 | CS Sfaxien | - | US Tataouine | 1:0 | ||||
| 1. Round | 14/11/2021 | CS Sfaxien | - | ES Métlaoui | 2:0 | ||||
| 7. Round | 21/11/2021 | CS Hammam-Lif | - | CS Sfaxien | 1:2 | ||||
| 8. Round | 03/03/2022 | ES Métlaoui | - | CS Sfaxien | 2:1 | ||||
| 9. Round | 06/03/2022 | CS Sfaxien | - | Espérance de Tunis | 1:0 | ||||
| 10. Round | 09/03/2022 | CS Sfaxien | - | US Ben Guerdane | 0:1 | ||||
| 14. Round | 18/04/2022 | CS Sfaxien | - | CS Hammam-Lif | 2:0 |
Tunisia