| 11. Round | 03/02/2021 | Tala'ea El Gaish SC | - | Al Mokawloon | 1:1 | ||||
| 14. Round | 17/02/2021 | Al Mokawloon | - | Aswan SC | 0:1 | ||||
| 19. Round | 22/04/2021 | Al Mokawloon | - | Wadi Degla SC | 1:0 |  |
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| 18. Round | 29/04/2021 | Zamalek | - | Al Mokawloon | 2:2 | ||||
| 20. Round | 05/05/2021 | Ceramica Cleopatra | - | Al Mokawloon | 1:1 | ||||
| 21. Round | 08/05/2021 | Al Mokawloon | - | El Entag El Harby | 1:1 | ||||
| 25. Round | 30/05/2021 | Smouha Sporting Club | - | Al Mokawloon | 2:2 | |
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| 27. Round | 28/06/2021 | ENPPI | - | Al Mokawloon | 1:1 | ||||
| 28. Round | 04/07/2021 | Al Mokawloon | - | Tala'ea El Gaish SC | 0:1 | ||||
| 26. Round | 08/07/2021 | Al Mokawloon | - | Al Ahly SC | 0:2 | ||||
| 24. Round | 16/07/2021 | Al Mokawloon | - | Pyramids FC | 0:2 | ||||
| 29. Round | 08/08/2021 | Al Masry Club | - | Al Mokawloon | 3:1 | ||||
| 30. Round | 12/08/2021 | Al Mokawloon | - | El Gouna | 2:1 | ||||
| 31. Round | 16/08/2021 | Aswan SC | - | Al Mokawloon | 1:2 | |
Egypt