| 1. Round | 26/10/2021 | Zamalek | - | ENPPI | 2:0 | ||||
| 2. Round | 30/10/2021 | ENPPI | - | Al Mokawloon | 3:2 | ||||
| 4. Round | 19/11/2021 | ENPPI | - | Smouha Sporting Club | 1:1 | ||||
| 8. Round | 09/02/2022 | ENPPI | - | Misr lel-Maqasah SC | 0:0 | ||||
| 9. Round | 16/02/2022 | Pharco FC | - | ENPPI | 1:0 | ||||
| 11. Round | 03/03/2022 | Al Masry Club | - | ENPPI | 2:2 |  |
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| 12. Round | 08/03/2022 | ENPPI | - | El Sharkia Lel Dokhan | 1:2 | ||||
| 13. Round | 16/03/2022 | ENPPI | - | Ceramica Cleopatra | 0:0 | ||||
| 19. Round | 15/05/2022 | Al Mokawloon | - | ENPPI | 2:2 | ||||
| 15. Round | 21/05/2022 | ENPPI | - | Al Ahly SC | 1:2 | ||||
| 20. Round | 24/05/2022 | ENPPI | - | Ghazl Al Mehalla | 2:2 | ||||
| 21. Round | 28/05/2022 | Smouha Sporting Club | - | ENPPI | 1:1 | ||||
| 22. Round | 18/06/2022 | ENPPI | - | Future FC | 1:2 | ||||
| 26. Round | 22/07/2022 | ENPPI | - | Pharco FC | 0:1 | ||||
| 30. Round | 08/08/2022 | Ceramica Cleopatra | - | ENPPI | 0:0 | ||||
| 31. Round | 17/08/2022 | ENPPI | - | Tala'ea El Gaish SC | 0:1 | ||||
| 33. Round | 27/08/2022 | ENPPI | - | Ismaily | 2:0 |
Egypt