| 18. Round | 06/04/2021 | Aswan SC | - | ENPPI | 1:0 | ||||
| 17. Round | 16/04/2021 | El Gouna | - | ENPPI | 1:0 | ||||
| 13. Round | 24/04/2021 | ENPPI | - | Al Ahly SC | 1:3 | ||||
| 19. Round | 02/05/2021 | ENPPI | - | Misr lel-Maqasah SC | 2:0 | ||||
| 20. Round | 06/05/2021 | Ghazl Al Mehalla | - | ENPPI | 1:0 | ||||
| 21. Round | 09/05/2021 | ENPPI | - | Ittihad El Iskandary | 0:0 | ||||
| 22. Round | 14/05/2021 | Zamalek | - | ENPPI | 3:1 | ||||
| 23. Round | 21/05/2021 | ENPPI | - | Wadi Degla SC | 0:0 | ||||
| 24. Round | 26/05/2021 | Ceramica Cleopatra | - | ENPPI | 0:2 | ||||
| 25. Round | 30/05/2021 | ENPPI | - | El Entag El Harby | 1:1 | ||||
| 26. Round | 16/06/2021 | National Bank SC | - | ENPPI | 2:3 | ||||
| 27. Round | 28/06/2021 | ENPPI | - | Al Mokawloon | 1:1 | ||||
| 28. Round | 04/07/2021 | Pyramids FC | - | ENPPI | 1:1 | ||||
| 29. Round | 09/08/2021 | ENPPI | - | Smouha Sporting Club | 0:0 | ||||
| 30. Round | 14/08/2021 | Al Ahly SC | - | ENPPI | 2:0 | ||||
| 31. Round | 17/08/2021 | ENPPI | - | Ismaily | 2:1 |  |
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| 32. Round | 20/08/2021 | ENPPI | - | Tala'ea El Gaish SC | 1:1 | ||||
| 33. Round | 23/08/2021 | Al Masry Club | - | ENPPI | 1:3 | ||||
| 34. Round | 28/08/2021 | ENPPI | - | El Gouna | 2:0 | |
Egypt