| 1. Round | 09/07/2022 | Atlas Guadalajara [Women] | - | UANL Tigres [Women] | 1:0 |  |
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| 2. Round | 16/07/2022 | Cruz Azul [Women] | - | UANL Tigres [Women] | 0:0 | ||||
| 3. Round | 26/07/2022 | UANL Tigres [Women] | - | Gallos Blancos [Women] | 4:0 | ||||
| 4. Round | 30/07/2022 | UANL Tigres [Women] | - | Club Necaxa [Women] | 2:0 | ||||
| 6. Round | 06/08/2022 | UANL Tigres [Women] | - | Puebla FC [Women] | 4:1 | ||||
| 7. Round | 16/08/2022 | Mazatlán FC [Women] | - | UANL Tigres [Women] | 0:8 | ||||
| 9. Round | 25/08/2022 | Santos Laguna [Women] | - | UANL Tigres [Women] | 1:4 | ||||
| 12. Round | 20/09/2022 | Deportivo Guadalajara [Women] | - | UANL Tigres [Women] | 1:0 | ||||
| 13. Round | 24/09/2022 | UANL Tigres [Women] | - | FC Juárez [Women] | 3:0 | ||||
| 14. Round | 26/09/2022 | Deportivo Toluca [Women] | - | UANL Tigres [Women] | 1:4 | ||||
| 15. Round | 01/10/2022 | UANL Tigres [Women] | - | CF Monterrey [Women] | 2:2 | ||||
| 16. Round | 17/10/2022 | Club León [Women] | - | UANL Tigres [Women] | 2:0 | ||||
| 17. Round | 25/10/2022 | UANL Tigres [Women] | - | Club Tijuana [Women] | 5:2 |
Colombia