| 1. Round | 24/08/2020 | Nea Salamina | - | AEK Larnaca | 1:2 | ||||
| 2. Round | 28/08/2020 | AEL Limassol | - | Nea Salamina | 2:1 | ||||
| 3. Round | 13/09/2020 | Nea Salamina | - | Enosis Neon Paralimni | 2:0 |  |
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| 6. Round | 03/10/2020 | Paphos FC | - | Nea Salamina | 1:0 | ||||
| 7. Round | 17/10/2020 | Nea Salamina | - | Anorthosis Famagusta | 1:4 |  |
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| 4. Round | 21/10/2020 | Doxa Katokopias | - | Nea Salamina | 2:0 | ||||
| 5. Round | 28/10/2020 | Nea Salamina | - | Ermis Aradippou | 0:1 | ||||
| 9. Round | 02/11/2020 | Nea Salamina | - | Ethnikos Achna | 1:1 | |
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| 10. Round | 08/11/2020 | Olympiakos Nikosia | - | Nea Salamina | 0:0 | ||||
| 17. Round | 02/01/2021 | Nea Salamina | - | Doxa Katokopias | 4:3 | ||||
| 18. Round | 05/01/2021 | Ermis Aradippou | - | Nea Salamina | 1:2 | ||||
| 19. Round | 11/01/2021 | Nea Salamina | - | Paphos FC | 2:0 | ||||
| 20. Round | 16/01/2021 | Anorthosis Famagusta | - | Nea Salamina | 2:0 | ||||
| 21. Round | 24/01/2021 | Nea Salamina | - | Apollon Limassol | 1:1 | ||||
| 22. Round | 31/01/2021 | Ethnikos Achna | - | Nea Salamina | 1:1 | ||||
| 23. Round | 05/02/2021 | Nea Salamina | - | Olympiakos Nikosia | 1:2 | ||||
| 26. Round | 19/02/2021 | Nea Salamina | - | Karmiotissa Polemidion | 4:0 |
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