| 3. Round | 08/08/2015 | KV Mechelen | - | Royal Mouscron-Péruwelz | 3:1 | ||||
| 4. Round | 15/08/2015 | Royal Mouscron-Péruwelz | - | Standard Liège | 1:1 | ||||
| 5. Round | 22/08/2015 | Waasland-Beveren | - | Royal Mouscron-Péruwelz | 3:3 | ||||
| 6. Round | 29/08/2015 | Royal Mouscron-Péruwelz | - | KV Kortrijk | 0:1 |  |
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| 7. Round | 11/09/2015 | Royal Mouscron-Péruwelz | - | Club Brugge KV | 2:1 | ||||
| 8. Round | 19/09/2015 | Sporting Lokeren | - | Royal Mouscron-Péruwelz | 1:2 | ||||
| 9. Round | 26/09/2015 | Royal Mouscron-Péruwelz | - | KV Oostende | 2:2 | ||||
| 10. Round | 03/10/2015 | Oud-Heverlee Leuven | - | Royal Mouscron-Péruwelz | 1:1 | ||||
| 14. Round | 01/11/2015 | RSC Anderlecht | - | Royal Mouscron-Péruwelz | 2:0 | ||||
| 15. Round | 06/11/2015 | Royal Mouscron-Péruwelz | - | SV Zulte Waregem | 2:2 | ||||
| 17. Round | 28/11/2015 | Sint-Truidense VV | - | Royal Mouscron-Péruwelz | 0:1 | ||||
| 18. Round | 05/12/2015 | Royal Mouscron-Péruwelz | - | KV Mechelen | 2:3 | ||||
| 19. Round | 12/12/2015 | KV Kortrijk | - | Royal Mouscron-Péruwelz | 1:3 | |
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| 28. Round | 27/02/2016 | KVC Westerlo | - | Royal Mouscron-Péruwelz | 2:2 |
Serbia