| 1. Round | 08/07/2017 | FK Khimki | - | Rotor Volgograd | 3:0 | ||||
| 2. Round | 15/07/2017 | Kuban Krasnodar (1928-2018) | - | FK Khimki | 0:1 | ||||
| 8. Round | 13/08/2017 | FK Khimki | - | Volgar Astrakhan | 0:1 | ||||
| 9. Round | 19/08/2017 | FK Khimki | - | Shinnik Yaroslavl | 0:3 |  |
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| 10. Round | 27/08/2017 | FK Khimki | - | Dinamo St. Petersburg | 0:1 | |
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| 11. Round | 02/09/2017 | FK Tyumen | - | FK Khimki | 2:2 |  |
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| 12. Round | 06/09/2017 | FK Khimki | - | Sibir Novosibirsk | 0:1 | ||||
| 13. Round | 10/09/2017 | FK Orenburg | - | FK Khimki | 5:2 | ||||
| 14. Round | 16/09/2017 | FK Khimki | - | FK Tambov | 1:1 | |
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| 15. Round | 24/09/2017 | Spartak Moskva 2 | - | FK Khimki | 0:1 | |
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| 17. Round | 07/10/2017 | Enisey Krasnoyarsk | - | FK Khimki | 4:1 | |
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| 18. Round | 14/10/2017 | FK Khimki | - | Zenit St. Petersburg 2 | 1:1 | ||||
| 19. Round | 21/10/2017 | Fakel Voronezh | - | FK Khimki | 0:1 | |
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| 20. Round | 28/10/2017 | FK Khimki | - | Kuban Krasnodar (1928-2018) | 2:1 | |
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| 21. Round | 04/11/2017 | Luch-Energiya Vladivostok | - | FK Khimki | 1:1 | |
Russia