| 1. Round | 22/08/2021 | TS Galaxy | - | Kaizer Chiefs | 0:0 | ||||
| 4. Round | 18/09/2021 | Kaizer Chiefs | - | Royal AM | 1:4 | ||||
| 5. Round | 26/09/2021 | Marumo Gallants | - | Kaizer Chiefs | 0:0 | ||||
| 7. Round | 16/10/2021 | Kaizer Chiefs | - | Chippa United | 4:0 | ||||
| 9. Round | 02/11/2021 | Kaizer Chiefs | - | Stellenbosch FC | 0:1 | ||||
| 15. Round | 12/12/2021 | Kaizer Chiefs | - | Sekhukhune United | 2:0 |  |
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| 16. Round | 19/12/2021 | Royal AM | - | Kaizer Chiefs | 1:0 | ||||
| 17. Round | 22/12/2021 | Kaizer Chiefs | - | Maritzburg United | 2:0 | |
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| 22. Round | 19/03/2022 | Kaizer Chiefs | - | Golden Arrows | 0:1 | ||||
| 25. Round | 16/04/2022 | Kaizer Chiefs | - | SuperSport United | 0:1 | ||||
| 26. Round | 23/04/2022 | Stellenbosch FC | - | Kaizer Chiefs | 1:0 | ||||
| 14. Round | 27/04/2022 | Golden Arrows | - | Kaizer Chiefs | 2:1 | ||||
| 13. Round | 30/04/2022 | Kaizer Chiefs | - | Cape Town City FC | 1:2 | ||||
| 29. Round | 14/05/2022 | Sekhukhune United | - | Kaizer Chiefs | 0:1 | ||||
| 30. Round | 21/05/2022 | Kaizer Chiefs | - | Moroka Swallows | 2:2 |
South Africa