| 3. Round | 28/08/2022 | Club NXT | - | RWD Molenbeek | 2:1 |  |
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| 4. Round | 03/09/2022 | Club NXT | - | K Beerschot VA | 1:2 | ||||
| 7. Round | 30/09/2022 | Excelsior Virton | - | Club NXT | 3:3 | |
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| 8. Round | 09/10/2022 | Club NXT | - | KRC Genk II | 3:1 | ||||
| 9. Round | 15/10/2022 | Lommel SK | - | Club NXT | 3:4 | |
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| 10. Round | 21/10/2022 | Club NXT | - | KMSK Deinze | 2:0 | ||||
| 11. Round | 29/10/2022 | FCV Dender EH | - | Club NXT | 3:2 | ||||
| 12. Round | 05/11/2022 | SK Beveren | - | Club NXT | 1:0 | ||||
| 15. Round | 25/11/2022 | Club NXT | - | FCV Dender EH | 4:1 |
Belgium