| 4. Round | 21/08/2016 | KAS Eupen | - | RSC Anderlecht | 2:2 |  |
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| 5. Round | 28/08/2016 | RSC Anderlecht | - | KAA Gent | 2:2 | ||||
| 6. Round | 11/09/2016 | RSC Anderlecht | - | Sporting Charleroi | 3:2 | ||||
| 7. Round | 18/09/2016 | KRC Genk | - | RSC Anderlecht | 0:2 | ||||
| 9. Round | 02/10/2016 | Standard Liège | - | RSC Anderlecht | 0:1 | ||||
| 11. Round | 23/10/2016 | Club Brugge KV | - | RSC Anderlecht | 2:1 | ||||
| 12. Round | 26/10/2016 | RSC Anderlecht | - | KV Mechelen | 2:0 | ||||
| 14. Round | 06/11/2016 | RSC Anderlecht | - | KV Oostende | 1:1 | ||||
| 23. Round | 25/01/2017 | KVC Westerlo | - | RSC Anderlecht | 2:4 | ||||
| 26. Round | 12/02/2017 | RSC Anderlecht | - | SV Zulte Waregem | 4:2 | ||||
| 29. Round | 04/03/2017 | KV Mechelen | - | RSC Anderlecht | 3:2 | ||||
| 30. Round | 12/03/2017 | RSC Anderlecht | - | Waasland-Beveren | 3:0 |
Belgium