| Round of 16 | 16/02/2022 | Deportivo Guastatoya | - | Club León | 0:2 |  |
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| Round of 16 | 23/02/2022 | Club León | - | Deportivo Guastatoya | 1:0 |
| Round of 16 | 16/02/2022 | Deportivo Guastatoya | - | Club León | 0:2 | |
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| Round of 16 | 23/02/2022 | Club León | - | Deportivo Guastatoya | 1:0 |
| Omar Andrés Fernández Frasica | |
| Born: | 11.02.1993 |
| Place of birth: |
Cundinamarca, 
Colombia |
| Nationality: |
Colombia
Mexico |
| Height: | 166 cm |
| Weight: | 60 kg |
| Position(s): | Left Midfielder Right Midfielder |
| Foot: | right |