| 1. Round | 27/03/2010 | CD Chivas | - | Colorado Rapids | 0:1 |  |
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| 2. Round | 02/04/2010 | Los Angeles Galaxy | - | CD Chivas | 2:0 | ||||
| 4. Round | 06/06/2010 | New York RB | - | CD Chivas | 1:0 | |
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| 4. Round | 27/06/2010 | CD Chivas | - | FC Dallas | 1:2 |  |
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| 5. Round | 04/07/2010 | CD Chivas | - | Philadelphia Union | 1:1 | ||||
| 5. Round | 11/07/2010 | Kansas City Wizards | - | CD Chivas | 0:2 | |
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| 6. Round | 01/08/2010 | CD Chivas | - | Columbus Crew | 3:1 | ||||
| 6. Round | 07/08/2010 | Toronto FC | - | CD Chivas | 2:1 | ||||
| 6. Round | 15/08/2010 | CD Chivas | - | Seattle Sounders | 0:0 |
El Salvador