| 1. Round | 13/02/2010 | Universidad Cesar Vallejo | - | Sporting Cristal | 2:3 | ||||
| 2. Round | 20/02/2010 | Sporting Cristal | - | FBC Melgar | 3:1 | ||||
| 3. Round | 03/03/2010 | Universitario de Deportes | - | Sporting Cristal | 1:2 |  |
|||
| 5. Round | 14/03/2010 | Alianza Atlético | - | Sporting Cristal | 0:0 | ||||
| 6. Round | 21/03/2010 | Sporting Cristal | - | Universidad San Martín | 0:4 | ||||
| 7. Round | 28/03/2010 | Sport Boys | - | Sporting Cristal | 1:2 |  |
|||
| 8. Round | 04/04/2010 | Sporting Cristal | - | Sport Huancayo | 4:1 | ||||
| 10. Round | 18/04/2010 | Sporting Cristal | - | CN Iquitos | 5:2 | |
|||
| 11. Round | 25/04/2010 | José Gálvez | - | Sporting Cristal | 1:1 | ||||
| 12. Round | 02/05/2010 | Juan Aurich | - | Sporting Cristal | 2:2 | ||||
| 13. Round | 08/05/2010 | Sporting Cristal | - | Total Chalaco | 1:0 | ||||
| 14. Round | 18/05/2010 | Alianza Lima | - | Sporting Cristal | 1:1 | ||||
| 15. Round | 22/05/2010 | Sporting Cristal | - | Cienciano | 0:1 | ||||
| 17. Round | 06/06/2010 | FBC Melgar | - | Sporting Cristal | 1:1 | ||||
| 19. Round | 13/06/2010 | León de Huánuco | - | Sporting Cristal | 6:0 |
Colombia