| 1. Round | 26/08/2018 | Xanthi FC | - | Panathinaikos | 0:1 | ||||
| 2. Round | 01/09/2018 | Panathinaikos | - | Lamia | 3:1 | ||||
| 5. Round | 29/09/2018 | Panathinaikos | - | PAS Giannina | 2:1 | ||||
| 6. Round | 06/10/2018 | Asteras Tripolis | - | Panathinaikos | 1:1 | ||||
| 7. Round | 20/10/2018 | Panathinaikos | - | Panionios GSS | 1:0 | ||||
| 8. Round | 29/10/2018 | PAOK Saloniki | - | Panathinaikos | 2:0 | ||||
| 9. Round | 03/11/2018 | Panathinaikos | - | AEK Athen | 0:0 | ||||
| 10. Round | 11/11/2018 | Olympiakos Piraeus | - | Panathinaikos | 1:1 | ||||
| 16. Round | 13/01/2019 | Panathinaikos | - | Xanthi FC | 2:2 | ||||
| 18. Round | 27/01/2019 | Panathinaikos | - | AE Lárissa | 1:1 | ||||
| 15. Round | 30/01/2019 | Panetolikos | - | Panathinaikos | 0:1 | ||||
| 19. Round | 03/02/2019 | Levadiakos | - | Panathinaikos | 0:0 | ||||
| 20. Round | 09/02/2019 | PAS Giannina | - | Panathinaikos | 1:0 | ||||
| 24. Round | 09/03/2019 | AEK Athen | - | Panathinaikos | 0:0 | ||||
| 25. Round | 17/03/2019 | Panathinaikos | - | Olympiakos Piraeus | 0:3 dec. | ||||
| 26. Round | 01/04/2019 | Apollon Smyrnis | - | Panathinaikos | 1:3 | ||||
| 29. Round | 21/04/2019 | Atromitos | - | Panathinaikos | 2:0 |
France