| 2. Round | 19/09/2020 | Panetolikos | - | AEK Athen | 0:2 | ||||
| 3. Round | 26/09/2020 | Olympiakos Piraeus | - | Panetolikos | 2:0 | ||||
| 4. Round | 03/10/2020 | Panetolikos | - | Asteras Tripolis | 1:1 | ||||
| 10. Round | 29/11/2020 | Panathinaikos | - | Panetolikos | 2:1 | ||||
| 13. Round | 19/12/2020 | Panetolikos | - | Apollon Smyrnis | 0:1 |  |
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| 14. Round | 03/01/2021 | Panetolikos | - | OFI Heraklion | 2:1 | ||||
| 15. Round | 06/01/2021 | AEK Athen | - | Panetolikos | 1:0 | |
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| 16. Round | 09/01/2021 | Panetolikos | - | Olympiakos Piraeus | 1:2 | ||||
| 22. Round | 14/02/2021 | Aris Saloniki | - | Panetolikos | 0:0 | |
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| 23. Round | 22/02/2021 | Panetolikos | - | Panathinaikos | 1:0 | ||||
| 24. Round | 28/02/2021 | AE Lárissa | - | Panetolikos | 1:0 | |
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| 25. Round | 07/03/2021 | Panetolikos | - | Volos NFC | 1:0 |
Mexico
Spain