| 3. Round | 22/01/2022 | Municipal Grecia | - | Jicaral | 1:0 |  |
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| 4. Round | 29/01/2022 | Jicaral | - | Santos de Guápiles | 1:0 | ||||
| 5. Round | 08/02/2022 | Sporting FC | - | Jicaral | 3:0 | ||||
| 11. Round | 01/04/2022 | CS Cartaginés | - | Jicaral | 0:0 | ||||
| 12. Round | 05/04/2022 | Jicaral | - | CS Herediano | 0:3 | |
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| 13. Round | 09/04/2022 | AD Guanacasteca | - | Jicaral | 3:2 | |
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| 16. Round | 24/04/2022 | Jicaral | - | Sporting FC | 2:0 | ||||
| 19. Round | 04/05/2022 | Jicaral | - | AD San Carlos | 2:1 |  |
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| 20. Round | 08/05/2022 | Deportivo Saprissa | - | Jicaral | 3:1 | ||||
| 21. Round | 11/05/2022 | Jicaral | - | Municipal Pérez Zeledón | 2:1 | ||||
| 22. Round | 15/05/2022 | Jicaral | - | CS Cartaginés | 4:3 |
Honduras