| 1. Round | 24/07/2021 | Levski Sofia | - | Slavia Sofia | 1:2 |  |
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| 2. Round | 31/07/2021 | Botev Vratsa | - | Levski Sofia | 2:0 | ||||
| 3. Round | 08/08/2021 | Levski Sofia | - | Arda Kardzhali | 0:2 | ||||
| 4. Round | 14/08/2021 | Levski Sofia | - | Tsarsko Selo Sofia | 3:1 | ||||
| 5. Round | 20/08/2021 | Botev Plovdiv | - | Levski Sofia | 3:1 |  |
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| 14. Round | 06/11/2021 | Slavia Sofia | - | Levski Sofia | 0:1 | ||||
| 15. Round | 22/11/2021 | Levski Sofia | - | Botev Vratsa | 0:0 | ||||
| 16. Round | 27/11/2021 | Arda Kardzhali | - | Levski Sofia | 0:0 | ||||
| 17. Round | 01/12/2021 | Tsarsko Selo Sofia | - | Levski Sofia | 0:1 | ||||
| 18. Round | 04/12/2021 | Levski Sofia | - | Botev Plovdiv | 2:0 | ||||
| 19. Round | 12/12/2021 | PFC Beroe | - | Levski Sofia | 1:1 | |
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| 21. Round | 26/02/2022 | CSKA 1948 Sofia | - | Levski Sofia | 0:2 | |
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| 23. Round | 13/03/2022 | PFC Ludogorets Razgrad | - | Levski Sofia | 2:1 | ||||
| 25. Round | 03/04/2022 | Pirin Blagoevgrad | - | Levski Sofia | 0:3 |
Spain