| 18. Round | 25/02/2018 | MFK Karviná | - | FC Fastav Zlín | 4:0 | ||||
| 19. Round | 03/03/2018 | Slovan Liberec | - | MFK Karviná | 2:2 | ||||
| 20. Round | 10/03/2018 | MFK Karviná | - | AC Sparta Praha | 1:1 | ||||
| 21. Round | 17/03/2018 | Sigma Olomouc | - | MFK Karviná | 1:1 | ||||
| 22. Round | 31/03/2018 | Zbrojovka Brno | - | MFK Karviná | 0:0 | ||||
| 23. Round | 08/04/2018 | MFK Karviná | - | 1. FC Slovácko | 0:0 | ||||
| 24. Round | 13/04/2018 | Slavia Praha | - | MFK Karviná | 3:2 | ||||
| 25. Round | 22/04/2018 | MFK Karviná | - | FK Teplice | 1:1 |  |
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| 26. Round | 28/04/2018 | Viktoria Plzeň | - | MFK Karviná | 2:0 | ||||
| 27. Round | 05/05/2018 | MFK Karviná | - | FK Dukla Praha | 1:3 | ||||
| 28. Round | 13/05/2018 | FK Jablonec | - | MFK Karviná | 2:1 |  |
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| 29. Round | 19/05/2018 | MFK Karviná | - | Baník Ostrava | 0:0 | |
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| 30. Round | 26/05/2018 | Vysočina Jihlava | - | MFK Karviná | 0:2 |
Czech Republic